Asked by: Crispin Hantzschmann
Asked in category: medical health, digestive disorders
Last Updated: 10th May 2024

What is the difference between total and direct bilirubins?

The liver attaches bilirubin to glucuronic acids, a glucose-derived chemical, and this is known as direct or conjugated bilirubin. Bilirubin that is not attached to the glucuronic acid, is called unconjugated bilirubin . Total bilirubin is all the bilirubin found in your blood.



Similar questions are asked: What is the difference in total bilirubin versus direct bilirubin.

The terms direct and indirect only refer to the way compounds are detected or measured in solution. The blood can measure the levels of total and direct Bilirubin, while indirect bilirubin can be calculated using the total and direct. Direct bilirubin and indirect bilirubin are both fat-soluble.

What happens if bilirubin direct is too high? High levels could indicate liver disease or damage. A higher level of directbilirubin may mean that your liver isn’t properly clearing bilirubin. Gilbert's syndrome is a common and benign cause of high bilirubin. It occurs when there is a shortage in an enzyme that breaks down bilirubin.

What is bilirubin directly?

Bilirubin is a substance that your body makes when it breaks down red blood cells. This is normal. Bilirubin bound to a protein (albumin in the blood) is called unconjugated Bilirubin. Conjugated, also known as direct, bilirubin travels through the liver to the small intestine.

Is there a danger level for direct bilirubin?

The normal bilirubin level is between 0.3 to 1.2 milligrams/deciliter (mg/dL). Any reading above 1.2 mg/dL will be considered high. Hyperbilirubinemia is a condition where there are high levels of bilirubin.