What is HIV resistance testing?

How does HIV resistance develop?

Drug resistance in HIV is due to mutations (changes) in the virus’s genetic structure. While many mutations occur at random, on a daily, basis, most are harmless. Most mutations are actually harmful to HIV because they reduce HIV's ability to infect CD4 cells and slow down its growth.

Second, what is the prevalence of HIV drug resistance? One study in 2004 estimated that 76.3% of Americans had some form of drug resistant HIV. South Korea's most recent study found that half of the HIV-positive population was multi-drug-resistant strains, and 10% were multi-class-resistant strains.

What time should patients be tested for antiretroviral resistance in addition?

Drug-resistance testing is a way to determine the role resistance plays in drug failure. It also maximizes the clinician's ability select active drugs for a new regimen. Resistance testing should be performed while the patient is on ART, or, if this is not possible, within four weeks of ART discontinuation (AII).

What does HIV resistance mean?

A small percentage of people have inborn resistance to HIV, which causes AIDS. The main mechanism acts as a coreceptor for HIV. The proportion of HIV-resistant people is less than 10%, according to estimates.